http://n.yam.com/afp/life/200809/20080919955658.html
研究:兒童時期患鼻炎與過敏 成年後易氣喘
法新社╱盧瑞珠 2008-09-19 14:05
(法新社巴黎十九日電)根據三份類似的研究結果,長期流鼻水、嬰兒期就吃止痛藥「樸熱息痛」、小時候就哮喘,都可能引發成年期氣喘。
其中一份研究發現,嬰兒一歲前服用不需醫師處方的止痛劑「樸熱息痛」,六到七歲前出現氣喘的可能性多出一半。
根據在三十一個國家收集到的二十多萬份兒童資料,研究同時發現,幼年期曾服用樸熱息痛的小孩,氣喘機率較高,愈常吃藥,風險愈高。
紐西蘭醫學研究所研究員畢司禮領導的研究指出,濕疹、鼻眼結膜炎(因過敏造成眼睛發炎)的機率同樣增加。報告刊登在英國醫學期刊「刺胳針」。
畢司禮和同事強調,他們的發現不代表父母應停止給孩子服用樸熱息痛。
他們表示:「樸熱息痛仍是兒童鎮痛止熱的優先選擇,但應該等到孩子高燒到攝氏三十八點五度才用。」
第二篇同樣發表在「刺胳針」的研究發現,二十歲到四十四歲之間成人首度氣喘發作,和鼻炎及過敏都有密切關連。
法國國家衛生暨醫學研究所人員,利用歐洲共同體健康調查的數據,將這些研究樣本分成四個族群:患鼻炎者、患過敏者、鼻炎與過敏皆有者、鼻炎與過敏皆無者。
經過近九年追蹤,發現既無鼻炎也無過敏者,只有百分之一會出現氣喘,有過敏現象者近百分之二會氣喘,長期流鼻水者出現氣喘的機率是百分之三,鼻炎和過敏都有的孩童,發生氣喘的可能性升高到百分之四。
第三同樣刊登在刺胳針特別號的研究,由亞利桑那大學的史坦主持,研究顯示,成年初期的慢性氣喘,與數種兒童時期的疾病有密切關連。
http://news.yahoo.com/s/afp/20080918/hl_afp/healthdiseaseasthma_080918233051;_ylt=AlwfubRxIifZX_qfisD.5qWJOrgF
Childhood conditions linked to adult asthma: studies
Thu Sep 18, 7:30 PM ET
PARIS (AFP) - A chronic runny nose, taking paracetamol in infancy, and wheezing as a child are all conditions linked to the onset of adulthood asthma, a trio of studies reported Friday.
Babies who took the over-the-counter pain reliever paracetamol in the first year of life were fifty percent more likely to show symptoms of asthma by the time they were six or seven years old, according to one of the studies.
Based on data collected on more than 200,000 children in 31 countries, the study also showed an increased risk of asthma symptoms in young children who had used the medication within the previous year -- the more frequently it was taken, the higher the risk.
Rates of eczema and rhinoconjunctivitis -- inflammation of the eye due to allergies -- also increased, according to the research, led by Richard Beasley of the Medical Research Institute in New Zealand and published in the British journal The Lancet.
Beasley and his colleagues stressed that their findings did not mean that parents should stop giving the drug.
"Paracetamol remains the preferred drug to relieve pain and fever in children," they said. "But it should be reserved for children with a high fever of 38.5 degrees Celsius (101.3 degrees Fahrenheit)."
A second study, also published in The Lancet, found that the first-time onset of asthma in adults aged 20-44 was closely linked to both rhinitis -- typically a runny nose caused by inflammation -- and allergies.
Using data from the European Community Health Survey, researchers at The National Institute of Health and Medical Research in France divided the subjects into four groups: those with rhinitis, with allergies, with both or neither.
The subjects were tracked over nearly a nine year period. Only one percent of the group that had neither ailment developed asthma, and almost twice as many of the allergy sufferers did.
More than three percent of adults with chronic runny noses wound up with asthma, and the rate jumped to nearly four percent for those who previously had both rhinitis and allergies.
A third study from the same special issue, led by Debra Stern of the University of Arizona in Tucson, showed a clear link between chronic asthma in early adulthood and several childhood conditions.
Follow up data on 850 infants covering a 20 year period showed, for example, that children who wheezed at age six were seven times more likely to become asthmatic.
The risk became 14 times greater for those who wheezed as adolescents.
"These findings identify a population at risk of chronic obstructive airway disease in early adulthood," noted Susanne Lau, a researcher at Charite University Medicine in Berlin.
"Whether therapeutic approaches at early preschool age can affect progression of the disease has yet to be established."
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