Mellow Demeanor May Stave Off Dementia
Jeanna Bryner, Senior Writer, LiveScience.com
People who are socially active and mellow may be less
likely to develop dementia, a new study finds.
Dementia is a loss of mental function, such as memory
and reasoning, that is severe enough to interfere with
everyday life. Several diseases can cause dementia,
including Alzheimer's (the most common cause of
dementia in the United States) and Parkinson's disease
as well as nutritional deficiencies, stroke and infections
that affect the brain.
About one in seven Americans aged 71 and older has
some form of dementia, the study researchers say.
However, scientists have yet to pinpoint a single cause of
dementia beyond the general associations with disease.
While genes play a role in some kinds of dementia,
dementia caused by Alzheimer's disease and some other
disorders results from a combination of genes, lifestyle
and other environmental factors, according to the National
Institute of Neurological Disorders and Stroke. For
instance, recently a team of scientists found that in mice
the gene Bmi1 controls the normal and pathological aging
of brain cells - a process that could lead to dementia.
The new study, which is detailed in the Jan. 20 issue of
the journal Neurology, reveals personality traits and
lifestyle could be major factors.
"The good news is, lifestyle factors can be modified as
opposed to genetic factors which cannot be controlled,"
said study researcher Hui-Xin Wang of the Karolinska
Institute in Stockholm, Sweden. "But these are early
results, so how exactly mental attitude influences risk for
dementia is not clear."
Personality and lifestyle
Wang and her colleagues followed more than 500 elderly
people for six years. None of the individuals, with an
average age of about 83, had dementia at the study's
start. Over the study period, 144 developed dementia.
The participants completed questionnaires about their
personality traits and lifestyle, including degree of
neuroticism (how easily the person gets distressed), level
of extroversion, amount of leisurely activities and the
richness of their social networks.
A person scoring low on neuroticism was characterized
as calm and self-satisfied, whereas those who were
easily distressed (high neuroticism) tended to be
emotionally unstable, negative and nervous.
Regarding personalities, outgoing individuals scored high
on the extroversion scale and were more socially active
and optimistic compared with individuals scoring low on
extroversion.
Stop the stress
Results showed that among people who were socially
isolated, those who were calm and relaxed were 50
percent less likely to develop dementia compared with
individuals who were prone to distress. Also, among the
outgoing extroverts, the dementia risk was also 50
percent lower for people who were calm compared with
those who were prone to distress.
The researchers say the ability to handle stress without
anxiety could help to explain the findings.
"In the past, studies have shown that chronic distress can
affect parts of the brain, such as the hippocampus,
possibly leading to dementia," Wang said, "but our
findings suggest that having a calm and outgoing
personality in combination with a socially active lifestyle
may decrease the risk of developing dementia even
further."
The study was supported by the Swedish Council for
Working Life and Social Research, Alzheimer Foundation
Sweden, Swedish Brain Power, Swedish Research
Council, Gamla Tjänarinnor Foundation, Fredrik and Ingrid
Thurings Foundation, Foundation for Geriatric Diseases
and Loo and Hans Osterman Foundation for Geriatric
Research at Karolinska Institute, and the Center for
Health Care Science at Karolinska Institute.
· 5 Ways to Beef Up Your Brain
· Video: Do You Have an Alzheimer's Barcode?
· Top 10 Mysteries of the Mind
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